# Cetrorelix

Canonical source: https://retacompare.com/encyclopedia/cetrorelix

Competitive GnRH receptor antagonist. Immediate suppression of LH surge without the agonist flare.

Reference facts

Also known asCetrotideCategoryGnRH & ReproductiveMechanism of actionCompetitive GnRH receptor antagonist. Immediate suppression of LH surge without the agonist flare.TargetsGnRH receptor (antagonist)Indications under research or approvedPrevention of premature LH surge during controlled ovarian stimulation in IVFRegulatory status (reference entry)FDA-approved (2000)Half-life~30 hours (3 mg dose)Sequence notesDecapeptide GnRH antagonist Ac-D-Nal-D-pClPhe-D-Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2.Molecular weight (Da)1431Originator / sponsorMerck Serono / EMD SeronoFirst reported1991
    Primary References

Cetrotide FDA label


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    This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.

## Sources

- Cetrotide FDA label: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021197s015lbl.pdf