Synthetic ACTH analog used diagnostically for adrenal stimulation testing.
Reference facts
- Also known as
- Cortrosyn, Tetracosactide, ACTH (1-24)
- Category
- Hormonal & Pituitary
- Mechanism of action
- Synthetic ACTH analog used diagnostically for adrenal stimulation testing.
- Targets
- MC2R
- Indications under research or approved
- Diagnosis of adrenal insufficiency
- Regulatory status (reference entry)
- FDA-approved
- Half-life
- ~15 minutes
- Sequence
- SYSMEHFRWGKPVGKKRRPVKVYP
- Sequence notes
- 24-residue N-terminal fragment of ACTH containing the full bioactivity in a less immunogenic molecule.
- Molecular weight (Da)
- 2933
- First reported
- 1965
Primary References
Explore research articles about Cosyntropin
This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.