# Cosyntropin

Canonical source: https://retacompare.com/encyclopedia/cosyntropin

Synthetic ACTH analog used diagnostically for adrenal stimulation testing.

Reference facts

Also known asCortrosyn, Tetracosactide, ACTH (1-24)CategoryHormonal & PituitaryMechanism of actionSynthetic ACTH analog used diagnostically for adrenal stimulation testing.TargetsMC2RIndications under research or approvedDiagnosis of adrenal insufficiencyRegulatory status (reference entry)FDA-approvedHalf-life~15 minutesSequenceSYSMEHFRWGKPVGKKRRPVKVYPSequence notes24-residue N-terminal fragment of ACTH containing the full bioactivity in a less immunogenic molecule.Molecular weight (Da)2933First reported1965
    Primary References

Cortrosyn FDA label


    Explore research articles about Cosyntropin


    This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.

## Sources

- Cortrosyn FDA label: https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/016750s029,016751s032lbl.pdf