# Glutathione (GSH)

Canonical source: https://retacompare.com/encyclopedia/glutathione

Major intracellular antioxidant; substrate for glutathione peroxidase, glutathione-S-transferase, and direct ROS quenching.

Reference facts

Also known asγ-L-Glutamyl-L-cysteinyl-glycineCategoryNeuropeptide & OtherMechanism of actionMajor intracellular antioxidant; substrate for glutathione peroxidase, glutathione-S-transferase, and direct ROS quenching.TargetsMultiple oxidative pathwaysIndications under research or approvedAcetaminophen overdose (NAC precursor pathway); research in liver disease, COPDRegulatory status (reference entry)Dietary supplement; IV/inhaled forms compoundedHalf-lifeMinutes (intact in plasma); hours intracellularlySequence notesTripeptide γ-Glu-Cys-Gly. The γ-glutamyl bond between Glu and Cys is non-canonical and the tripeptide is therefore not represented by single-letter sequence.Molecular weight (Da)307First reported1888
    Primary References

Forman et al., Mol Aspects Med 2009 (GSH)


    Explore research articles about Glutathione (GSH)


    This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.

## Sources

- Forman et al., Mol Aspects Med 2009 (GSH): https://pubmed.ncbi.nlm.nih.gov/18796312/