# Insulin Lispro

Canonical source: https://retacompare.com/encyclopedia/insulin-lispro

Rapid-acting prandial insulin; faster onset and shorter duration than regular insulin.

Reference facts

Also known asHumalog, AdmelogCategoryHormonal & PituitaryMechanism of actionRapid-acting prandial insulin; faster onset and shorter duration than regular insulin.TargetsInsulin receptorIndications under research or approvedDiabetes — prandial insulinRegulatory status (reference entry)FDA-approved (1996)Half-life~1 hourSequenceGIVEQCCTSICSLYQLENYCNSequence notesRapid-acting insulin: B-chain residues Pro28 and Lys29 swapped, reducing dimerization and accelerating absorption.Molecular weight (Da)5808PDB accession1LPHOriginator / sponsorEli LillyFirst reported1994
    Primary References

Humalog FDA label


    Explore research articles about Insulin Lispro


    This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.

## Sources

- Humalog FDA label: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020563s201lbl.pdf