Cationic membrane-disrupting helix with broad-spectrum activity against Gram-positive, Gram-negative bacteria, fungi, viruses.
Reference facts
- Also known as
- Cathelicidin antimicrobial activity
- Category
- Antimicrobial
- Mechanism of action
- Cationic membrane-disrupting helix with broad-spectrum activity against Gram-positive, Gram-negative bacteria, fungi, viruses.
- Targets
- Microbial membranes
- Indications under research or approved
- Research
- Regulatory status (reference entry)
- Not FDA-approved
- Half-life
- Minutes
- Sequence
- LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
- Sequence notes
- Same molecule as the immune entry; listed separately for indexing under antimicrobial peptides.
- Molecular weight (Da)
- 4493
- PDB accession
- 2K6O
- First reported
- 1995
Primary References
Explore research articles about LL-37 (Antimicrobial)
This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.