# Macimorelin

Canonical source: https://retacompare.com/encyclopedia/macimorelin

Oral GHS-R1a agonist used as a single-dose diagnostic test for adult GH deficiency.

Reference facts

Also known asMacrilen, AEZS-130CategoryGrowth Hormone & GhrelinMechanism of actionOral GHS-R1a agonist used as a single-dose diagnostic test for adult GH deficiency.TargetsGHS-R1aIndications under research or approvedDiagnosis of adult growth hormone deficiencyRegulatory status (reference entry)FDA-approved (2017)Half-life~4 hoursSequence notesOrally active tripeptidomimetic ghrelin receptor agonist.Molecular weight (Da)535Originator / sponsorAeterna Zentaris / Novo NordiskFirst reported2013
    Primary References

Garcia et al., JCEM 2018 (Macimorelin pivotal)


    Explore research articles about Macimorelin


    This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.

## Sources

- Garcia et al., JCEM 2018 (Macimorelin pivotal): https://pubmed.ncbi.nlm.nih.gov/29635330/