Mimics CNTF activity via gp130 receptor signaling; promotes neurogenesis in hippocampal subgranular zone.
Reference facts
- Also known as
- Ciliary Neurotrophic Factor mimetic peptide
- Category
- Nootropic & Cognitive
- Mechanism of action
- Mimics CNTF activity via gp130 receptor signaling; promotes neurogenesis in hippocampal subgranular zone.
- Targets
- gp130 (CNTF receptor)
- Indications under research or approved
- Preclinical research — neurodegeneration, neurogenesis
- Regulatory status (reference entry)
- Not FDA-approved
- Half-life
- Hours
- Sequence
- DGGLAG
- Sequence notes
- Hexapeptide CNTF mimetic with N-acetyl and C-amide modifications.
- Molecular weight (Da)
- 503
- First reported
- 2010
Primary References
Explore research articles about P21
This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.