# P21

Canonical source: https://retacompare.com/encyclopedia/p21

Mimics CNTF activity via gp130 receptor signaling; promotes neurogenesis in hippocampal subgranular zone.

Reference facts

Also known asCiliary Neurotrophic Factor mimetic peptideCategoryNootropic & CognitiveMechanism of actionMimics CNTF activity via gp130 receptor signaling; promotes neurogenesis in hippocampal subgranular zone.Targetsgp130 (CNTF receptor)Indications under research or approvedPreclinical research — neurodegeneration, neurogenesisRegulatory status (reference entry)Not FDA-approvedHalf-lifeHoursSequenceDGGLAGSequence notesHexapeptide CNTF mimetic with N-acetyl and C-amide modifications.Molecular weight (Da)503First reported2010
    Primary References

Blanchard et al., Neuropeptides 2010 (P21 neurogenesis)


    Explore research articles about P21


    This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.

## Sources

- Blanchard et al., Neuropeptides 2010 (P21 neurogenesis): https://pubmed.ncbi.nlm.nih.gov/20570337/