Anxiolytic peptide that modulates GABA, serotonin and BDNF in animal models without sedation.
Reference facts
- Also known as
- TP-7
- Category
- Nootropic & Cognitive
- Mechanism of action
- Anxiolytic peptide that modulates GABA, serotonin and BDNF in animal models without sedation.
- Targets
- GABA-A allosteric modulation (indirect), BDNF expression
- Indications under research or approved
- Approved Russia (generalized anxiety); not US-approved
- Regulatory status (reference entry)
- Not FDA-approved
- Half-life
- Several hours (intranasal)
- Sequence
- TKPRPGP
- Sequence notes
- Heptapeptide. Synthetic analog of the immunomodulator tuftsin (TKPR) with a stabilizing PGP tail.
- Molecular weight (Da)
- 752
- Originator / sponsor
- Originally Institute of Molecular Genetics, Moscow
- First reported
- 1991
Primary References
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This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.