GnRH super-agonist with desensitization profile similar to Leuprolide.
Reference facts
- Also known as
- Trelstar, Decapeptyl
- Category
- GnRH & Reproductive
- Mechanism of action
- GnRH super-agonist with desensitization profile similar to Leuprolide.
- Targets
- GnRH receptor
- Indications under research or approved
- Advanced prostate cancer, Central precocious puberty
- Regulatory status (reference entry)
- FDA-approved (2000)
- Half-life
- ~3 hours (depot formulations)
- Sequence notes
- Decapeptide pyroGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2; D-Trp at position 6 confers super-agonist activity.
- Molecular weight (Da)
- 1311
- Originator / sponsor
- Verity Pharmaceuticals / Ipsen
- First reported
- 1980
Primary References
Explore research articles about Triptorelin
This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.