Albumin Binding — Peptide Glossary | RetatrutideCompare

The attachment of a peptide to albumin (the most abundant protein in blood plasma). Albumin binding shields the peptide from rapid kidney clearance, extending its half-life. Many long-acting peptide drugs are deliberately engineered with a fatty-acid tail that anchors them to albumin - semaglutide, cagrilintide, and eloralintide all use this strategy.
Category: Peptide Chemistry