# How Fast Can You Lose Weight on Peptide Therapy?

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Weight Loss & Metabolism


    The rate of weight loss with peptide-based therapies varies depending on the specific peptide, dosage, and individual factors. Clinical trial data provide general timelines for what researchers have observed. With GLP-1 agonists like semaglutide, participants typically lose 5-7% of body weight in the first 12 weeks, reaching approximately 15% by 68 weeks. With Retatrutide, the most potent triple agonist, weight loss appears faster, reaching approximately 24% by 48 weeks at the highest dose.


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