AOD-9604 Research: What 25 Studies Show (2026) | RetatrutideCompare

AOD-9604 — 25 studies indexed on PubMed. Originally developed as a lipolytic / anti-obesity agent; later studied for cartilage repair via influence on chondrocyte proliferation. Half-life: ~38 minutes. FDA status: Not FDA-approved (cosmetic GRAS in some jurisdictions).

PubMed search-result count last fetched 2026-06-18. Records may include reviews, laboratory work, and animal studies; this is not a clinical trial count or a measure of efficacy.

Inspect the PubMed query and results

How many studies have been published on AOD-9604?

There are approximately 25 studies indexed on PubMed that mention AOD-9604 (Anti-Obesity Drug 9604, hGH 177-191), based on a search last updated 2026-06-18.

Is AOD-9604 FDA-approved?

FDA status: Not FDA-approved (cosmetic GRAS in some jurisdictions).

How does AOD-9604 work?

Originally developed as a lipolytic / anti-obesity agent; later studied for cartilage repair via influence on chondrocyte proliferation.

Originally developed as a lipolytic / anti-obesity agent; later studied for cartilage repair via influence on chondrocyte proliferation.

Reference facts

Also known as
Anti-Obesity Drug 9604, hGH 177-191
Category
Healing & Tissue Repair
Mechanism of action
Originally developed as a lipolytic / anti-obesity agent; later studied for cartilage repair via influence on chondrocyte proliferation.
Targets
β3-adrenergic receptor (proposed), Chondrocyte signaling
Indications under research or approved
Failed Phase 2 obesity (2007); research in osteoarthritis
Regulatory status (reference entry)
Not FDA-approved (cosmetic GRAS in some jurisdictions)
Half-life
~38 minutes
Sequence
YLRIVQCRSVEGSCGF
Sequence notes
16-residue C-terminal fragment of human growth hormone (177-191) with an added N-terminal tyrosine; intramolecular disulfide between Cys7-Cys13.
Molecular weight (Da)
1815
Originator / sponsor
Originally Metabolic Pharmaceuticals (Australia)
First reported
2002

Primary References

Explore research articles about AOD-9604

This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.