Glutathione (GSH) Research: What 203,467 Studies Show (2026) | RetatrutideCompare

Glutathione (GSH) — 203,467 studies indexed on PubMed. Major intracellular antioxidant; substrate for glutathione peroxidase, glutathione-S-transferase, and direct ROS quenching. Half-life: Minutes (intact in plasma); hours intracellularly. FDA status: Dietary supplement; IV/inhaled forms compounded.

PubMed search-result count last fetched 2026-06-18. Records may include reviews, laboratory work, and animal studies; this is not a clinical trial count or a measure of efficacy.

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How many studies have been published on Glutathione (GSH)?

There are approximately 203,467 studies indexed on PubMed that mention Glutathione (GSH) (γ-L-Glutamyl-L-cysteinyl-glycine), based on a search last updated 2026-06-18.

Is Glutathione (GSH) FDA-approved?

FDA status: Dietary supplement; IV/inhaled forms compounded.

How does Glutathione (GSH) work?

Major intracellular antioxidant; substrate for glutathione peroxidase, glutathione-S-transferase, and direct ROS quenching.

Major intracellular antioxidant; substrate for glutathione peroxidase, glutathione-S-transferase, and direct ROS quenching.

Reference facts

Also known as
γ-L-Glutamyl-L-cysteinyl-glycine
Category
Neuropeptide & Other
Mechanism of action
Major intracellular antioxidant; substrate for glutathione peroxidase, glutathione-S-transferase, and direct ROS quenching.
Targets
Multiple oxidative pathways
Indications under research or approved
Acetaminophen overdose (NAC precursor pathway); research in liver disease, COPD
Regulatory status (reference entry)
Dietary supplement; IV/inhaled forms compounded
Half-life
Minutes (intact in plasma); hours intracellularly
Sequence notes
Tripeptide γ-Glu-Cys-Gly. The γ-glutamyl bond between Glu and Cys is non-canonical and the tripeptide is therefore not represented by single-letter sequence.
Molecular weight (Da)
307
First reported
1888

Primary References

Explore research articles about Glutathione (GSH)

This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.