Gonadorelin Research: What 37,172 Studies Show (2026) | RetatrutideCompare

Gonadorelin — 37,172 studies indexed on PubMed. Native gonadotropin-releasing hormone. Pulsatile administration stimulates LH/FSH; continuous administration desensitizes the pituitary. Half-life: ~4 minutes. FDA status: FDA-approved (Factrel, Lutrepulse — partially discontinued).

PubMed search-result count last fetched 2026-06-18. Records may include reviews, laboratory work, and animal studies; this is not a clinical trial count or a measure of efficacy.

Inspect the PubMed query and results

How many studies have been published on Gonadorelin?

There are approximately 37,172 studies indexed on PubMed that mention Gonadorelin (GnRH, LHRH), based on a search last updated 2026-06-18.

Is Gonadorelin FDA-approved?

FDA status: FDA-approved (Factrel, Lutrepulse — partially discontinued).

How does Gonadorelin work?

Native gonadotropin-releasing hormone. Pulsatile administration stimulates LH/FSH; continuous administration desensitizes the pituitary.

Native gonadotropin-releasing hormone. Pulsatile administration stimulates LH/FSH; continuous administration desensitizes the pituitary.

Reference facts

Also known as
GnRH, LHRH
Category
GnRH & Reproductive
Mechanism of action
Native gonadotropin-releasing hormone. Pulsatile administration stimulates LH/FSH; continuous administration desensitizes the pituitary.
Targets
GnRH receptor
Indications under research or approved
Diagnostic GnRH stimulation test; hypothalamic amenorrhea (pulsatile pump)
Regulatory status (reference entry)
FDA-approved (Factrel, Lutrepulse — partially discontinued)
Half-life
~4 minutes
Sequence
QHWSYGLRPG
Sequence notes
Decapeptide pyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (Q at position 1 = pyroglutamate).
Molecular weight (Da)
1182
First reported
1971
Origin
Sequenced by Andrew Schally and Roger Guillemin (Nobel Prize 1977).

Primary References

Explore research articles about Gonadorelin

This is an educational reference, not medical advice. Research findings do not establish safety or efficacy for self-administration. Consult the primary sources for study populations, limitations, and current regulatory status.