# What Is Compounded Tirzepatide?

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Compounded Peptides · 2026-01-08


    Compounded tirzepatide refers to a preparation of the GLP-1/GIP dual agonist peptide produced by a licensed compounding pharmacy rather than manufactured by Eli Lilly. During the FDA-declared tirzepatide shortage, 503A and 503B compounding pharmacies were permitted under limited enforcement discretion to prepare customized versions of the drug for individual patients. These preparations typically differ from branded Mounjaro and Zepbound in dosage, formulation vehicle, and sometimes the inclusion of additional ingredients such as vitamin B12 or lipotropic adjuncts. As of 2026 the regulatory environment surrounding compounded tirzepatide has changed substantially, following the FDA's removal of tirzepatide from the drug shortage list and subsequent litigation by Eli Lilly against several telehealth compounders.


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